Technology

The physician selection committee and the core imaging lab will determine the optimal route for delivery of the GATE™ AVS. An animation of trans-jugular delivery and an image of trans-atrial delivery are shown below.

There is an on-going effort to develop a trans-femoral delivery system.

Trans-jugular Approach: Animation

Trans-atrial Approach: Image

GATE™ System Overview

Ventricular View (ØRV)

The GATE™ System is intended to treat functional tricuspid regurgitation (FTR)/tricuspid insufficiency by replacing the function of a patient’s dysfunctional native tricuspid valve with a bio-prosthetic atrioventricular valved stent (AVS). The AVS is designed to restore valve function in patients presenting with FTR/tricuspid insufficiency without the need for conventional, open-heart surgery.

The GATE™ System is comprised of an Atrioventricular Valved Stent (AVS), delivery catheter and related accessories. The AVS is being developed in a range of sizes, including Ø40mm, Ø44mm, Ø48mm, and Ø52mm, with a maximum profile height of 23mm.

Atrial View (ØRA)

Height

The AVS is of tri-leaflet design and includes patented partially dehydrated tissue technology, a self-expanding Nitinol stent and special fabric to encourage fibrous ingrowth of biological material to aid in inter-chamber sealing of the device. The design of the AVS is intended to capture the native annulus and leaflets of the dysfunctional tricuspid valve.